Clinical R&D Vivariums

This 7,500 GSF project’s delivery is a traditional design-bid-build FFP/GMax method.  Acting as the Client’s Authorized Owner’s Rep / Engineering Project Manager, TCS’s services for this project included design, construction and engineering project management through facility validation and operations.  The facility has 100% HEPA filtered SA & EA, two isolation rooms, a laboratory with an egg incubation room, vaccination/challenge room, secure hardened select agent containment room, 100% HEPA filtered air, N+1 critical MEP equipment, fogging & facility wash-down capabilities, 96 stainless steel negatively pressurized isolation cages, necropsy areas, a preparation area, change rooms and ancillary support areas.  Equipment includes class II bio-safety cabinets, CO2 double-stack incubators, ultra-low temperature freezers, an autoclave and stainless steel necropsy tables.  

This 5,600 GSF fast-track design/build project was completed from initial conception through project operational validation and turnover to the client in 12 months. TCS provided full development and engineering project management services for the design/build RFP, General Contractor / Design Team selection and subsequent design and construction management of this facility.  The facility has 100% HEPA filtered SA & EA, with TCS’s custom designed dual pre & secondary EA filters with dander/feather traps for prolonged Bag-In/Bag-Out HEPA filter service life, N+1 critical MEP equipment, fogging & facility wash-down capabilities, 96 stainless steel negatively pressurized isolation cages, necropsy areas, a preparation area, change rooms, a small laboratory and ancillary support areas.  

This 8,250 GSF facility was designed and constructed to include appropriate bio-containment and bio-security features along with building automation controls to support bio-exclusion, challenge and discovery studies.   The 100% SA / EA HEPA filtered exhaust system includes N+1 true fan-wall technology, an energy recovery system and a full re-circulation UV animal watering system.  The facility also includes eight isolation rooms, an isolation cell with five individual isolators for discovery studies, animal support areas, clean and dirty cage washing rooms, two treatment rooms, technician space and ancillary support areas.  Stainless steel collapsible animal holding pens, an animal watering system and an isolated waste disposal system was included in the facility. 

TCS was tasked with leading the design and implementation of renovations to an existing mamalian facility to receive 50 mobile fan powered avian isolators that were scheduled to be transferred from our client’s sister site. The existing positive pressure cascade was converted to a negative cascade with a new N+1 exhaust system.  A new panel was installed on emergency power to power .  

This project was delivered under a fast-tracked design-build method utilizing TCS’s extensive knowledge of HVAC design and installation procedures to revamp the existing HVAC systems for reconfiguration necessary to meet the Client’s corporate biosecurity design guidelines as well as all necessary modifications and upgrades to meet USDA guidelines.  Acting as the Client’s Engineering Project Manager, TCS’s services for this project included design and construction management, through facility validation and operations.  The converted isolator room contains 100% Bag-In / Bag-Out HEPA filtered air, N+1 critical MEP equipment, fogging and facility wash-down capabilities.  TCS provided the custom designed pre/secondary filter isolator caging and room filter banks with isolation dampers for filter change-outs without loss of operational capabilities, as well as the custom designed isolator caging dander/feather traps for increasing the longevity of the filter replacements.